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Be aware that tadalafil may interact with some medicines. consult with your health care provider in case you are taking any other drugs, especially any of the following: nitroglycerin-type drugs for the heart or chest pain such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, even if these are only taken occasionally; alpha blockers, such as alfuzosin (uroxatral®), doxazosin (cardura®), prazosin (minipress®), or terazosin (hytrin®), used to treat high blood pressure or an enlarged prostate; Tramadol is an analgesic that is used to treat moderate to moderately severe pain. Mechanism of action is the decreasing of brain's perception and response to pain and reducing of the size or magnitude of the pain signal passed from one nerve to another.

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